PetMeds® Frontline Plus Questions

Some of the more common recent questions I’ve received in the clinic regarding f and its use for flea and tick prevention in pets. A big concern I often receive is the quality of Frontline Plus being carried by online pharmacies like 1800petmeds and whether it is the same as those used and sold by veterinary offices. The truth of the matter is that Frontline Plus is a prepackaged product by Merial, and is the exact same one carried by 1-800-PetMeds as your local veterinarian. Improper application is one of the most common reasons for flea treatment failure

Another common question is, “Why does my pet still have fleas after applying Frontline?” (after a few consecutive months. The most common reasons for flea treatments failing is typically because of improper application, or more commonly failure to treat the environment of the pet, including the home and yard; where 80% of the flea life cycle occurs. Along the same line, some products, however will work better on some pets than others. So, if there are still fleas even after properly treating the home and using Frontline Plus for several months, I would suggest having your house professionally treated by an exterminator and/or change to a different product such as Advantage.

If a pet still has fleas, many veterinarians will use the product more frequently than once monthly, sometimes as often as once every 2-3 weeks. However, this process is often considered to be “off label use,” and I would not use the product this way unless first speaking with your pet’s veterinarian. If a client is currently using a different topical such as Revolution or Advantage, it is safe to change to Frontline Plus after 3-4 weeks from the date of last application of the other product. While Frontline Plus is labeled as waterproof, I usually advise clients to wait at least 24 to 48 hours before bathing their pet. Side effects to Frontline Plus are rare but may include hair loss/skin irritation at site of application, (rarely) digestive upset, (and even rarer) immunological reactions of the blood or neurological reactions like seizures. Again, these are very rare, as most pets tolerate this product quite well.

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127 Comments

  1. Would I be able to give him the rest of the dose today?

  2. HI Rachael. I usually dont suggest redosing the front line, even at lower dose, for at least 2 weeks after the initial dose. In future, it may be best to consider an oral prescription medication for fleas if you need additional coverage; i.e such as oral comfortis, etc from 1800petmeds.

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