PetMeds® K9 Advantix II: Flea Control for Dogs

Filed under Dr. Dym's Vet Blog
How does one provide protection to their dogs against 5 major disease carrying external parasites such as fleas, ticks, mosquitoes, lice and biting flies?  The new and improved K9 Advantix 2 product kills 98% of adult fleas are killed within 12 hours, and the trio of main ingredients also repels many of these parasites as well.

Being water proof is also a wonderful benefit, especially in those dogs who swim or are bathed often. Of course the best side effect with this product is the wonderful broad spectrum parasite control which is highly superior to most other products. Rare reactions include sensitivity at the site of application, digestive upset and even less commonly neurological reactions.

Pet owners should wait at least 1-2 hours for K9 Advantix II to dry before allowing dogs around cats

One of the main client concerns with K9 Advantix II is its use in households with cats. When this product first came out it was recommended that it be used only in those households without cats, but with additional research it was found that it was safe to use this product on dogs who live with cats, as long as one allows 1-2 hours for the product to adequately dry on your dog, before reintroducing them to the cats in the home. Please note, this product is NOT to be used directly on cats due to potential severe toxicity.

If you have been using K9 Advantix on your dog, are you planning on switching to the K9 Advantix II?

Need help choosing the correct flea medication for your pet? Try our Flea & Tick Comparison chart.


  1. D Morgan
    Posted May 9, 2011 at 7:56 am | Permalink

    How about a REFUND from the manufacturer of this over-priced K9Advantix (version 1) for it’s inefficiency!! I have yet to see it keep the fleas off my 2 dogs for a solid month yet!! I’ve purchased a 12-month supply, and re-apply every 3 weeks…

  2. admin
    Posted May 9, 2011 at 9:47 am | Permalink

    Hi there, we’re sorry to hear the product does not seem to have worked. If you purchased K9 Advantix from us, one of our Customer Care reps (1-800-738-6337) will be more than happy to help and refund your purchase.

  3. Joni Stankaitis
    Posted July 25, 2013 at 3:58 pm | Permalink

    I used Advantix II on my dogs (black lab and dachshund) and it worked wonders on both of them, but especially the black lab who was chewing herself raw. Within 2 days of the application, she was no longer biting and scratching, and within a week, her hair was growing back.

  4. Dr. Michael Dym, VMD veterinarian
    Posted July 25, 2013 at 11:10 pm | Permalink

    Thanks for your comments and experience.

  5. VAFlatlander
    Posted September 9, 2013 at 2:02 pm | Permalink

    My dog is a Pomeranian Mix.

    He scratches or bites on himself all the time.

    He is about 33 lbs.

  6. Dr. Michael Dym, VMD veterinarian
    Posted September 9, 2013 at 11:27 pm | Permalink

    Try antihistamine such as benadryl at dose of 1 mg per pound twice daily. Yucca intensive by azmira also may help as well from 1800petmeds. Add fatty acid like be well to meals

  7. bETH
    Posted August 27, 2014 at 8:15 pm | Permalink

    What is the K9 advantix II dosage per pound for dogs?

  8. Dr. Michael Dym, VMD veterinarian
    Posted August 28, 2014 at 6:03 pm | Permalink

    Dont know off top of my head. I follow package recommendations for product based on weight….. For exact number, see the product label. a 1800petmeds pharmacist also may help

  9. Nancy
    Posted September 6, 2014 at 8:16 am | Permalink

    My Chihuahua sleeps with me. Is it safe for him to still sleep with me after applying K9 Advantix II? Also is my cat safe.

  10. Dr. Michael Dym, VMD veterinarian
    Posted September 8, 2014 at 3:38 pm | Permalink

    As long as product dries you are fine

  11. Posted June 10, 2015 at 4:38 am | Permalink

    320166 388671As a result you

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