PetMeds® Addressing Canine Incontinence

Older dogs may develop urinary incontinence as a result of muscles loosening around the urethra
One of the more common urinary complaints of older dogs is when animal guardians start discovering puddles of urine where dogs rest or sleep at night. This common problem is often due to a weakness of the nerves around the urethra, which is the outflow tract of the bladder.  When the muscles around the urethra are loose or lax, then urine leakage can occur when a dog is resting or asleep.

While this problem is fairly common in spayed and neutered pets, there are several effective prescription medicines that can help.  For years we used to use low doses of estrogen hormone with a product known as stilbestrol or DES.  However, because of the small risk of hormonal side effects, another drug called phenylpropanolamine or Proin replaced DES as the most common drug of choice in treating incontinent pets.   Most dogs’ urine leaking can be adequately controlled with Proin in my experience, which acts to tighten the muscles around the urethra.

However, it is important to have a full medical evaluation, including urine analysis and possibly blood work to rule out other potential underlying causes and urinary infections first before prescribing medicines for urine leaking. Other holistic products such as HomeoPet Leaks No More can also be tried, but in my experience these other drugs are much less effective in controlling urinary incontinence or leaking in dogs.

Related Posts


  1. maybe one of these will help zoey.

  2. Dr. Michael Dym, VMD veterinarianJanuary 29, 2011 at 11:50 am

    Proin or stilbesterol are often the prescription drugs of choice,.

  3. Hi,

    My female is three months and urinate in her sleep and sometimes while playing give way to urinate without having to take the position of urination.

    Thank you ,


  4. Dr. Michael Dym, VMD veterinarianDecember 6, 2012 at 3:06 pm

    Should have vet exam and urine analysis to start to make sure no medical issues or infection.

Leave a Comment