Using Pet med Soloxine to Help Hypothyroidism in Dogs and Cats

Soloxine is commonly used as hormone therapy for pets with hypothyroidism
Hypothyroidism (low thyroid) is one of the most common hormonal conditions seen in dogs. While this condition can be seen in any mixed or pure breed, common symptoms include:

– Weight gain (without an increase in appetite)
– Lethargy
– Cold intolerance (heat seeking)
– Dull/dry hair coat
– Hair loss
– Recurrent skin or ear infections
– Problems with the nervous or musculoskeletal system

Diagnosis of this condition is usually made by a full thyroid profile performed at the veterinary office, including measurement of T4, Free T4, and thyroid autoantibodies. It is important for veterinarians not to just routinely run a T4 when screening dogs for hypothyroidism, as one can over diagnose this condition when measuring only T4.

Once properly diagnosed, treatment is usually with the prescription medication levothyroxine (name brand Soloxine). In my experience and opinion Soloxine usually offers superior results in normalizing thyroid levels than the cheaper generic brands. Side effects of Soloxine are rare but may include diarrhea and/or vomiting. This is usually seen only when dosing is too high as determined by measuring thyroid blood levels at follow-up visits.

If Soloxine is not helping a pet’s skin condition, than it is important to have a full veterinary follow-up evaluation to see if dosing is appropriate, as well as to evaluate for other diseases such as allergic skin disease or other hormonal conditions.

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  1. No where in these symptoms is seizures mentioned. My miniature poodle developed seizures and changed behavior. He did not bark, seemed to have lessened awareness of surroundings and weakend hind quarters. A lab panel revealed hypo-thyroidism. My vet prescribed soloxin and his condition steadily improved.I was thrilled when he started to bark again.
    Further search on the internet said seizures are common with hypo-thyroidism and many Vets are not aware of this(I hope this is not true)
    He still experiences tics, may have epilepsy-vet not sure. Hate to hurt anyones feelings but, thanx again to internet, have run across a product with antioxidents and Chinese herbs that is for nerve and liver health. The mini seizures or tics have decreased greatly. I chose this remedy over my vet’s decision to use phenobarbitol.(it is heck, having an RN for a client or patient0

  2. Dr. Michael Dym, VMD veterinarianMay 31, 2012 at 4:14 pm

    Thanks for sharing.

  3. Thank for sharing this. A friend of mine had already told me about but the others are mostly new! Thanks again. ( )

  4. I have a 7 year old siamese who suddenly became obese, yet eats very little. This all began after a vicious stray attacked her private parts and ripped them open. I took her to the vet who sewed her up satistfactorily. However, immediately, she gained weight – fast and furious. She has all the symptoms: ear problems, dry flaky skin, lethargy, she is now so heavy she is miserable and I can barely pick her up. I once had a hyperthryoid cat that had to have surgery, and i am hoping that Soloxine will help. I know I need a typroid T exam (I am hypothryoid myself and take the same meds. Is there hope for Sweet Pea? It is terrible to watch her blow up and be so uncomfortable.

  5. Dr. Michael Dym, VMD veterinarianOctober 22, 2013 at 10:15 pm

    Hi Karen. I would not assume hypothyroid. This condition is rare in cats but worth checking along with other hormonal problem like Cushings disease, etc. I would strongly recommend with homeopathic vet who can address this on a holistic level from both diet and treatment perspective. To learn more go to as well as my website Many homeopathic vets do offer phone consultations as do I nationwide.

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